Thermo Fisher Scientific CSK Polyclonal Antibody
CSK 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체. Western blot과 면역세포화학(ICC/IF)에 적합. 인간 반응성, 액상 형태, 0.5 mg/mL 농도. 세포 성장 및 신호 조절 연구용.
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–0.3 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide corresponding to the C terminus amino acids EQLEHIKTHELHL (aa 438–450) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2084018 |
Product Specific Information
- Predicted to react with bovine and canine based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 32,000.
Target Information
CSK is a tyrosine kinase that downregulates SRC oncoprotein activity through phosphorylation of its carboxy terminus. The CSK gene may function as an antioncogene and plays a key role in regulating cell growth, differentiation, migration, and immune responses.
CSK phosphorylates tyrosine residues in the C-terminal tails of Src-family kinases such as LCK, SRC, HCK, FYN, LYN, CSK, and YES1. It is expressed ubiquitously as a ~50 kDa cytosolic protein, with a fraction localized to lipid rafts via interaction with PAG (Csk-binding protein).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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