Thermo Fisher Scientific Calreticulin Polyclonal Antibody
Calreticulin 단백질을 검출하는 Thermo Fisher Scientific의 폴리클로날 항체. Western blot, IHC, ICC, IP 등 다양한 어플리케이션에 사용 가능. Chicken IgY 기반, 고순도 항원 친화 크로마토그래피 정제. PBS/BSA 버퍼에 보관하며 -20°C에서 안정적 저장 가능.
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Thermo Fisher Scientific Calreticulin Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:2,000 | View 12 publications |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunocytochemistry (ICC/IF) | Assay-dependent | View 2 publications |
| Immunoprecipitation (IP) | Assay-dependent | View publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Dog, Hamster, Human, Mouse, Rabbit, Rat |
| Published Species | Amphibian, Human, Mouse, Rabbit, Rat |
| Host / Isotype | Chicken / IgY |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic Peptide: D(399)EK EE DEE ESPGQAKD(414) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2228457 |
Product Specific Information
PA1-903 detects calreticulin from human, rat, mouse, hamster, rabbit, and canine tissues.
It has been successfully used in Western blot, immunoprecipitation, immunocytochemistry, and immunofluorescence procedures.
By Western blot, this antibody detects an ~60 kDa protein representing calreticulin and an ~120 kDa unidentified protein from rat brain extract.
PA1-903 immunizing peptide corresponds to amino acid residues 399–414 from mouse calreticulin.
The immunizing peptide (Cat. # PEP-017) is available for use in neutralization and control experiments.
Target Information
Calreticulin (Calr) is a calcium-binding chaperone that promotes folding, oligomeric assembly, and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle.
Calr interacts transiently with most monoglucosylated glycoproteins synthesized in the ER and with the DNA-binding domain of NR3C1, mediating its nuclear export.
It may also play a role in maternal gene expression regulation and oocyte maturation through calcium homeostasis regulation.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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