Thermo Fisher Scientific Influenza A PA Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Recommended positive controls: Influenza virus (A/WSN/1933(H1N1))-infected DF-1 cell lysates.
• Store product as a concentrated solution.
• Centrifuge briefly prior to opening the vial.

Target Information

Influenza viruses consist of three types (A, B, and C), which make up three of the five genera in the Orthomyxoviridae family. Commonly known as the flu, influenza strains can infect both birds and mammals.
Influenza viruses form roughly spherical particles with a viral envelope containing two main types of glycoproteins (hemagglutinin and neuraminidase), surrounding the central core of the viral RNA genome and associated proteins.
The influenza virus genome is segmented into seven to eight fragments of negative-sense RNA, each encoding different viral proteins. Influenza A virus contains eight single-stranded, negative-sense RNAs. Each RNA associates with viral RNA-dependent RNA polymerase consisting of PA, PB1, and PB2 proteins.
The PA protein plays a key role in the “cap-snatching” mechanism via its endonuclease activity, essential for cRNA-dependent viral RNA synthesis.

⚠ WARNING
This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.