Thermo Fisher Scientific CD68 Monoclonal Antibody (OTI12C6), TrueMAB
인간 CD68 단백질을 인식하는 마우스 단클론 항체로, Western blot에 최적화되어 있습니다. 동결건조 형태로 제공되며 PBS 완충액에 보관됩니다. 재구성 후 약 1 mg/mL 농도로 사용 가능하며, 연구용으로만 사용됩니다.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI12C6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 22–319 of human CD68 produced in SF9 cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predominantly expressed on intracellular lysosomes of monocytes and macrophages, and to a lesser extent in dendritic cells and granulocytes. It is involved in phagocytic activity, lysosomal metabolism, and cell-cell or cell-pathogen interactions.
CD68 expression is observed in interdigitating reticulum cells, histiocytic lymphoma, histiocytosis, AML, and granulocytic sarcoma. Elevated expression has been reported in CD34+ cells in various human malignancies, including several acute myeloid leukemia studies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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