Thermo Fisher Scientific Adenosine Deaminase Monoclonal Antibody (CL0176)
Human ADA 단백질을 인식하는 Mouse monoclonal antibody로 Western blot, IHC, ICC/IF에 적합. 고순도 Protein A 정제 및 PBS/glycerol buffer 구성. 연구용으로 adenosine 대사 및 T-cell 조절 연구에 활용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 2–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CL0176 |
| Immunogen | Recombinant protein corresponding to Human Adenosine Deaminase |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2637201 |
Product Specific Information
Immunogen sequence:
SDNQPEGMIS ESLDNLESMM PNKVRKIGEL VRYLNTNPVG GLLEYARSHG FAAEFKLVDQ SGPPHEPKFV YQAKVGGRWF PAVCAHSKKQ GKQEAADAAL RVLIGENEKA ERMGFTEVTP VTGASLRRTM LLLSRSPEA
Highest antigen sequence identity to orthologs:
- Mouse: 86%
- Rat: 85%
Target Information
Adenosine deaminase catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
It plays an essential role in purine metabolism and adenosine homeostasis, modulating extracellular adenosine signaling and contributing to cellular signaling events.
It may act as a positive regulator of T-cell coactivation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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