Thermo Fisher Scientific Aquaporin 4 Monoclonal Antibody (CL0178)
Aquaporin 4 단백질을 인식하는 Thermo Fisher Scientific의 Mouse monoclonal 항체. Western blot, IHC, ICC 등 다양한 응용에 적합. Human 시료에 반응하며 Protein A로 정제됨. 장기 보관은 -20°C 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1 µg/mL | - |
| Immunohistochemistry (IHC) | - | 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1000 | - |
| Immunocytochemistry (ICC/IF) | - | 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CL0178 |
| Immunogen | Recombinant protein corresponding to Human Aquaporin 4 (amino acids 253–323) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.00 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2637202 |
Product Specific Information
Immunogen sequence:
CPDVEFKRRF KEAFSKAAQQ TKGSYMEVED NRSQVETDDL ILKPGVVHVI DVDRGEEKKG KDQSGEVLSS VAntigen sequence identity:
Mouse – 93%, Rat – 92%Epitope:
Binds to an epitope located within the peptide sequence FKRRFKEAFS, as determined by overlapping synthetic peptides.
Target Information
Aquaporin 4 (AQP4), also known as mercurial-insensitive water channel, is localized to the sarcolemma of fast-twitch skeletal muscle fibers.
Aquaporins (AQPs) are integral membrane water channel proteins that facilitate water transport across cell membranes and are conserved across animals, plants, and bacteria.
Mammalian AQPs are designated AQP0–AQP10 and can coexist within the same cell. While most AQPs are selective for water, AQP3, AQP7, AQP9, and one AQP10 transcript are also permeable to urea and glycerol.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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