
Thermo Fisher Scientific TRPM7 Polyclonal Antibody
TRPM7 단백질을 인식하는 Sheep Polyclonal Antibody로, Western blot 및 IHC에 사용 가능. 인간 및 랫트 반응성. 합성 펩타이드 면역원 사용, 비결합형 형태. 연구용으로만 사용 가능.
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Thermo Fisher Scientific TRPM7 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 10–50 µg/mL |
| Immunohistochemistry (IHC) | 10–50 µg/mL |
| Miscellaneous PubMed (Misc) | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the 4th cytoplasmic loop of human TRPM7 (LTRPC7) conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 500 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: TRPM7.
Target Information
TRPCs are mammalian homologs of the Drosophila transient receptor potential (trp) protein and function as ion channels mediating capacitative calcium entry into cells.
TRP-PLIK is a dual-function protein acting both as an ion channel and a kinase.
As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium.
As a kinase, it can phosphorylate itself and other substrates.
The kinase activity is essential for channel function, dependent on intracellular ATP and influenced by kinase mutants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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