Thermo Fisher Scientific CHMP2B Recombinant Rabbit Monoclonal Antibody (ARC2404)
CHMP2B 단백질을 인식하는 토끼 유래 재조합 단일클론 항체로, Western blot, IHC, ELISA에 적합합니다. 인간, 마우스, 랫트 반응성을 가지며, 고순도의 Affinity chromatography 정제 제품입니다. 연구용으로 안정적인 -20°C 보관이 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC2404 |
| Immunogen | A synthetic peptide corresponding to amino acids 114–213 of human CHMP2B (Q9UQN3) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.23 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897799 |
Product Specific Information
- Positive Samples: HeLa, PC-12, C2C12, RD, SH-SY5Y, Mouse brain
- Immunogen sequence:
KKMDPQKTLQ TMQNFQKENM KMEMTEEMIN DTLDDIFDGS DDEEESQDIV NQVLDEIGIE ISGKMAKAPS AARSLPSAST SKATISDEEI ERQLKALGVD
Target Information
CHMP2B, also known as CHMP2.5 or vacuolar protein-sorting-associated protein 2-2, is a 213 amino acid cytosolic protein. It is widely expressed in brain, heart, skeletal muscle, small intestine, pancreas, lung, placenta, and leukocytes. CHMP2B associates directly with CHMP2A and VPS4 for the disassembly of the ESCRT-III complex.
Defects in the CHMP2B gene have been linked to chromosome 3–associated frontotemporal dementia (FTD3).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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