Thermo Fisher Scientific Uroplakin 1B Monoclonal Antibody (UPK1B, 3081)
인간 Uroplakin 1B 단백질을 인식하는 Mouse 모노클로날 항체로, IHC(P) 및 Peptide Array에 사용 가능. Protein A/G 정제, PBS 버퍼 내 0.05% BSA 및 sodium azide 함유. 4°C 보관, 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UPK1B, 3081 |
| Immunogen | Recombinant fragment (around aa 109–229) of human Uroplakin 1B (UPK1B) protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 minutes at room temperature.
- Staining of formalin-fixed tissues requires heating in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
Uroplakin 1B is a component of the asymmetric unit membrane (AUM), a specialized biomembrane elaborated by terminally differentiated urothelial cells. It may play an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or stabilizing the apical membrane through AUM/cytoskeletal interactions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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