Thermo Fisher Scientific WDR5 Monoclonal Antibody (2C2)
WDR5 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 ELISA에 적합합니다. 비결합형 액상 형태이며, 사람 단백질에 반응합니다. 연구용으로만 사용 가능하며, -20°C에서 보관 권장됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2C2 |
| Immunogen | WDR5 (NP_060058, 16 a.a. approximately 120 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
QPTPSSSATQ SKPTPVKPNY ALKFTLAGHT KAVSSVKFSP NGEWLASSSA DKLIKIWGAY DGKFEKTISG HKLGISDVAW SSDSNLLVSA SDDKTLKIWD VSSGK
Target Information
Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2).
Acts as a molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation by promoting disassembly of transcriptional regulatory complexes.
Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruitment of EGLN1/PHD2 to the HSP90 pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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