Thermo Fisher Scientific ITGB8 Polyclonal Antibody
Human, Mouse, Rat에서 반응하는 ITGB8 폴리클로날 항체로, Western blot과 ELISA에 적합합니다. Rabbit IgG 유래 비결합 항체이며, Affinity Chromatography로 정제되었습니다. PBS/glycerol buffer에 보관하며 -20°C에서 안정적으로 저장 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 43–320 of human ITGB8 (NP_0022051) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.26 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2808854 |
Product Specific Information
Immunogen sequence:
EDNRCASSNA ASCARCLALG PECGWCVQED FISGGSRSER CDIVSNLISK GCSVDSIEYP SVHVIIPTEN EINTQVTPGE VSIQLRPGAE ANFMLKVHPL KKYPVDLYYL VDVSASMHNN IEKLNSVGND LSRKMAFFSR DFRLGFGSYV DKTVSPYISI HPERIHNQCS DYNLDCMPPH GYIHVLSLTE NITEFEKAVH RQKISGNIDT PEGGFDAMLQ AAVCESHIGW RKEAKRLLLV MTDQTSHLAL DSKLAGIVVP NDGNCHLKNN VYVKSTTM
Positive Samples: SGC-7901, 293T, HeLa
Cellular Location: Membrane, Single-pass type I membrane protein
Target Information
ITGB8 (Integrin beta 8) is a member of the integrin beta chain family and is a single-pass type I membrane protein with a VWFA domain and four cysteine-rich repeats. This protein noncovalently binds to an alpha subunit to form a heterodimeric integrin complex. Integrin complexes mediate cell-cell and cell-extracellular matrix interactions and this complex plays a role in human airway epithelial proliferation. Alternatively spliced variants encoding different isoforms have been described, though not all variants are fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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