Thermo Fisher Scientific ITGB8 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 43-320 of human ITGB8 (NP_0022051) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ITGB8 (Integrin beta 8),uniProtId:P26012-1,ncbiNodeId:9606,antigenRange:43-320,antigenLength:769,antigenImageFileName:PA5-97052_ITGB8_Integrin_beta_8_P26012-1_Rabbit.svg,antigenImageFileNamePDP:PA5-97052_ITGB8_Integrin_beta_8_P26012-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.26 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2808854

Product Specific Information

Immunogen sequence: EDNRCASSNA ASCARCLALG PECGWCVQED FISGGSRSER CDIVSNLISK GCSVDSIEYP SVHVIIPTEN EINTQVTPGE VSIQLRPGAE ANFMLKVHPL KKYPVDLYYL VDVSASMHNN IEKLNSVGND LSRKMAFFSR DFRLGFGSYV DKTVSPYISI HPERIHNQCS DYNLDCMPPH GYIHVLSLTE NITEFEKAVH RQKISGNIDT PEGGFDAMLQ AAVCESHIGW RKEAKRLLLV MTDQTSHLAL DSKLAGIVVP NDGNCHLKNN VYVKSTTM; Positive Samples: SGC-7901, 293T, HeLa; Cellular Location: Membrane, Single-pass type I membrane protein

Target Information

ITGB8 (Integrin beta 8) is a member of the integrin beta chain family and is a single-pass type I membrane protein with a VWFA domain and four cysteine-rich repeats. This protein noncovalently binds to an alpha subunit to form a heterodimeric integrin complex. In general, integrin complexes mediate cell-cell and cell-extracellular matrix interactions and this complex plays a role in human airway epithelial proliferation. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.