Thermo Fisher Scientific NOTCH1 Recombinant Rabbit Monoclonal Antibody (ARC0285)
NOTCH1 단백질을 타깃으로 하는 Thermo Fisher의 재조합 토끼 단클론 항체 ARC0285. Western blot, ELISA, IP 등에 적합하며 인간 및 마우스 시료에 반응. 고순도 Affinity Chromatography 정제, 액상 형태로 안정적 보관 가능.
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Thermo Fisher Scientific NOTCH1 Recombinant Rabbit Monoclonal Antibody (ARC0285)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
| Immunoprecipitation (IP) | 0.5 µg–4 µg antibody for 200 µg–400 µg extracts |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0285 |
| Immunogen | Synthetic peptide corresponding to amino acids 2456–2555 of human Notch1 (P46531) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849159 |
Product Specific Information
Immunogen sequence:
ILPQESPALP TSLPSSLVPP VTAAQFLTPP SQHSYSSPVD NTPSHQLQVP EHPFLTPSPE SPDQWSSSSP HSNVSDWSEG VSSPPTSMQS QIARIPEAFK
Target Information
The Notch gene family encodes transmembrane proteins with multiple cysteine-rich EGF-like repeats in the extracellular region. Four Notch genes (Notch1–4) are described in mammals and are involved in the differentiation of the nervous system and other tissues. Delta and Serrate act as ligands for Notch1. Mature Notch proteins form heterodimeric receptors composed of an extracellular subunit (NEC) and a transmembrane subunit (Ntm) derived from cleavage of Notch pre-proteins.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: MA5-35256_NOTCH1_P46531-1_Rabbit.svg, MA5-35256_NOTCH1_P46531-1_Rabbit_PDP.jpeg)
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