Thermo Fisher Scientific Phospho-SRC3 (Ser857) Polyclonal Antibody
SRC3 단백질의 Ser857 인산화 형태를 특이적으로 검출하는 rabbit polyclonal antibody. Western blot에 적합하며, 인간 및 생쥐 시료에 반응. 고순도 정제 및 안정적 PBS/glycerol buffer로 제공. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NCOA3 (Accession Q9Y6Q9), corresponding to amino acid residues around phosphorylated Ser857 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817587 |
Product Specific Information
Antibody detects endogenous levels of SRC3 only when phosphorylated at Ser857.
Target Information
AIB1-AC3 recognizes AIB1, a member of the SRC-1 family of nuclear receptor coactivators with an apparent molecular weight of 160 kDa.
The AIB1 gene has been mapped to region 20q12 and has been shown to be amplified in breast tumors and pancreatic cancer cell lines.
AIB1 interacts in a ligand-dependent fashion with the estrogen receptor to enhance estrogen-dependent transcriptional gene activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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