Thermo Fisher Scientific Phospho-NDRG1 (Ser330) Polyclonal Antibody
NDRG1 단백질의 Ser330 인산화 형태를 특이적으로 검출하는 Rabbit Polyclonal 항체. Western blot 및 IHC(Paraffin) 적용 가능. Human, Mouse, Rat 반응성. 고순도 액상 형태로 -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
- Publications: References
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- Publications: References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NDRG1 (Accession Q92597), corresponding to amino acid residues around phosphorylated Ser330 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817589 |
Product Specific Information
Antibody detects endogenous levels of NDRG1 only when phosphorylated at Ser330.
Target Information
NDRG1 is a 394 amino acid cytoplasmic protein belonging to the NDRG family. It interacts with APO A-I and A-II and plays a role in HDL-mediated cholesterol transport, stress responses, hormone responses, cell growth and differentiation.
Defect in NDRG1 causes Charcot-Marie-Tooth disease type 4D (CMT4D), characterized by reduced nerve conduction velocities, segmental demyelination and remyelination with onion bulb formations, slowly progressive distal muscle atrophy and weakness, absent deep tendon reflexes, and hollow feet.
NDRG1 plays a growth inhibitory role and serves as a marker of differentiation. It is expressed in placental membranes, prostate, kidney, small intestine, ovary, colon, and luminal border cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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