
Thermo Fisher Scientific beta-2 Adrenergic Receptor Polyclonal Antibody
Human, Mouse, Rat 반응성을 가진 beta-2 Adrenergic Receptor 폴리클로날 항체로, Rabbit IgG 호스트에서 생산됨. IHC(Paraffin) 실험에 적합하며, 고순도(>95%) 항원 친화 크로마토그래피로 정제됨. 장기 보관 시 -20°C에서 보관 권장.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 201–250 of Human AR-beta2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803226 |
Product Specific Information
- Multiple bands are observed at 47 kDa, 68 kDa (glycosylated), and 95 kDa (dimer).
- Purity is >95% by SDS-PAGE.
Target Information
Adrenergic receptors (ARs) are members of the 7-transmembrane domain G-protein-coupled receptor superfamily that bind the endogenous catecholamines epinephrine and norepinephrine.
Pharmacological, structural, and molecular cloning data indicate significant heterogeneity within this receptor family.
Nine receptor subtypes have been identified thus far, including:
- Three alpha-1 AR subtypes (1A/D, 1B, 1C)
- Three alpha-2 ARs (2A, 2B, 2C)
- Three beta AR subtypes (1, 2, 3)
ARs are involved in the onset or maintenance of several disease states such as:
- Hypertension
- Cardiac dysfunction (congestive heart failure, ischemia, arrhythmias)
- Diabetes
- Glaucoma
- Depression
- Impotence
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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