Thermo Fisher Scientific TRPM5 Polyclonal Antibody
TRPM5 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot 및 Immunohistochemistry에 사용 가능. 인간 및 비인간 영장류 반응성. 동결건조 형태로 장기 보관 시 -20°C에서 안정적. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunohistochemistry (IHC)
- Tested Dilution: 1:1,000
Miscellaneous PubMed (Misc)
- Publication: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from human TRPM5 conjugated to blue carrier protein was used as the antigen |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: TRPM5.
Target Information
This gene encodes a member of the transient receptor potential protein family, which is a diverse group of proteins with structural features typical of ion channels.
TRPM5 plays an important role in taste transduction and functions as a calcium-activated, non-selective cation channel that carries Na⁺, K⁺, and Cs⁺ ions equally well, but not Ca²⁺ ions.
It is activated by lower concentrations of intracellular calcium and inhibited by higher concentrations.
TRPM5 is highly temperature-sensitive, showing steep increases of inward currents between 15°C and 35°C.
This gene is located within the Beckwith-Wiedemann syndrome critical region-1 on chromosome 11p15.5 and is imprinted, expressed exclusively from the paternal allele.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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