Thermo Fisher Scientific Human Angiogenin Synthetic Peptide
인간 Angiogenin 중심부 15 아미노산 서열 기반 합성 펩타이드. 항체 PA5-34422의 블로킹 펩타이드로 사용 가능. 혈관신생 관련 연구에 적합하며, 액상 형태로 제공. PBS 버퍼(pH 7.2, 0.1% BSA) 내 보관, -20°C 저장 권장.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to a 15 amino acid sequence near the center of human Angiogenin (ANG).
PEP-1464 can be used as a blocking peptide with polyclonal antibody PA5-34422.
Target Information
Angiogenin (ANG or ANG I) plays a key role in neovascularization and new blood vessel formation. It is structurally similar to pancreatic ribonuclease A and functions as a tRNA-specific ribonuclease that inhibits protein synthesis by hydrolyzing cellular tRNAs. ANG interacts with endothelial cell-surface actin, leading to cytoskeletal changes. It is implicated in solid tumor development, and its antagonists can inhibit tumor growth. Defects in ANG are associated with susceptibility to amyotrophic lateral sclerosis type 9 (ALS9), linking ANG genetically to both ALS and Parkinson’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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