Thermo Fisher Scientific TEF1 Polyclonal Antibody
TEF1 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, Flow Cytometry에 사용 가능. Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제된 액상 시약. TEF1의 핵 내 발현 연구에 적합.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific TEF1 Polyclonal Antibody
Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:400 |
| Flow Cytometry (Flow) | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein within human TEF1 (aa 1–150/426) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2913484 |
Product Specific Information
- Positive Control: Mouse liver tissue lysate, mouse skeletal muscle tissue lysate, rat skeletal muscle tissue, human fetal skeletal muscle tissue, HeLa cells
- Subcellular Location: Nucleus
Target Information
TEF1 (Transcriptional enhancer factor 1) is a nuclear protein belonging to the TEA/ATTS domain family. It is expressed in various cell types and regulates the expression of numerous genes. TEF family members have a conserved DNA-binding domain, and TEF-1 binds to GT-IIC, SphI/II, and M-CAT sequences. It also interacts with the proximal regulatory element (PRE) of transforming growth factor-alpha, which is overexpressed in many cancers. TEF-1 represses transcription in placental cells and is phosphorylated by PKC isozymes, reducing its DNA-binding capability. This suggests a role in PKC inhibition and tumorigenesis. Dimerization of TEF-1 may be essential for its function in gene transcription regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.