Thermo Fisher Scientific DUSP5 Monoclonal Antibody (OTI1D8), TrueMAB
인간, 생쥐, 랫트 반응성을 가진 DUSP5 단클론 항체로 Western blot에 최적화됨. 항체는 무보존 Lyophilized 형태이며, 재구성 후 1 mg/mL 농도로 사용 가능. MAP kinase 경로 연구용으로 적합하며, 핵 내 DUSP5 단백질 검출에 유용.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 125–384 of human DUSP5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The DUSP5 gene encodes a dual specificity protein phosphatase that inactivates target kinases by dephosphorylating phosphoserine/threonine and phosphotyrosine residues. It negatively regulates MAP kinases involved in cellular proliferation and differentiation. DUSP5 specifically inactivates ERK1, is highly expressed in pancreas and brain, and localizes to the nucleus.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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