Thermo Fisher Scientific SARS-CoV/SARS-CoV-2 NP Chimeric Recombinant Human Monoclonal Antibody (CR3018 (03-018))

Applications

Immunocytochemistry (ICC/IF)

• Tested Dilution: Assay-dependent

ELISA

• Tested Dilution: Assay-dependent

Product Specifications

Product Specific Information

This antibody binds the amino acid residues between 11-19 of the N protein of the SARS-CoV as well as SARS-CoV-2 (COVID-19) nucleocapsid protein.

Target Information

Human coronaviruses are the major cause of upper respiratory tract illness in humans, such as the common cold. Coronaviruses are positive-stranded RNA viruses, featuring the largest viral RNA genomes known to date (27–31 kb). The first step in coronavirus infection is binding of the viral spike protein, a 139-kDa protein, to certain receptors on host cells. The spike protein is the main surface antigen of the coronavirus.

The most prominent protein in the culture supernatants infected with SARS virus is a 46 kDa nucleocapsid protein, suggesting that the nucleocapsid protein is a major immunogen useful for early diagnostics. SARS-CoV-2 Nucleocapsid Protein is associated with nucleic acid and is the most abundant protein for coronavirus. Due to its strong immunogenicity, the SARS-CoV-2 Nucleocapsid Protein has potential value for diagnostic applications.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.