
Thermo Fisher Scientific Phospho-PAR4 (Thr163) Polyclonal Antibody
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Phospho-PAR4 (Thr163) 폴리클로날 항체로 인간, 마우스, 원숭이, 랫트에서 반응. Western blot에 적합하며 항원 친화 크로마토그래피로 정제됨. BSA와 글리세롤을 포함한 HEPES 버퍼에 보관. -20°C에서 저장 권장.
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Applications
- Western Blot (WB)
Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues surrounding Thr163 of human PAR-4 (Thr155 in rat and Thr156 in mouse) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10979599 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
This gene encodes a tumor suppressor protein that selectively induces apoptosis in cancer cells through intracellular and extracellular mechanisms.
- Intracellular mechanism: Inhibition of pro-survival pathways and activation of Fas-mediated apoptosis.
- Extracellular mechanism: Binding of secreted form to GRP78 on the cell surface, activating the extrinsic apoptotic pathway.
This gene is located on the unstable human chromosomal 12q21 region and is often deleted or mutated in different tumors. The encoded protein also plays an important role in the progression of age-related diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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