Thermo Fisher Scientific CD36 Monoclonal Antibody (FA6-152), Biotin
CD36 단백질을 인식하는 FA6-152 클론의 Biotin 결합 단일클론 항체입니다. 인간 시료에 반응하며 IHC, ICC/IF, Flow cytometry, IP, 기능 및 억제 분석에 사용됩니다. CD36의 생물학적 활성을 차단하며, 콜라겐/트롬보스폰딘 결합을 억제합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Frozen) (IHC (F)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:50 |
| Flow Cytometry (Flow) | 1:50 |
| Immunoprecipitation (IP) | 1:50 |
| Functional Assay (Functional) | 1:50 |
| Inhibition Assays (IA) | 1:50 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | FA6-152 |
| Immunogen | 20-weeks-old fetal erythrocytes |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 100 µg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
| RRID | AB_3093167 |
Additional Formats
Product Specific Information
Monoclonal antibody FA6-152 blocks the biological activity of CD36 by inhibiting collagen/thrombospondin binding. This antibody agglutinates fetal but not adult erythrocytes.
Target Information
CD36, also known as scavenger receptor class B member 3, is a membrane protein expressed on macrophages, platelets, and adipocytes. It is involved in lipid metabolism, inflammation, and atherosclerosis, recognizing ligands such as oxidized LDL, long-chain fatty acids, and apoptotic cells. CD36 functions as a thrombospondin receptor and mediates cytoadherence of Plasmodium falciparum-infected erythrocytes. Mutations in CD36 cause platelet glycoprotein deficiency, and alternative splicing variants are known. Diseases associated include Platelet Glycoprotein IV Deficiency and Coronary Heart Disease 7.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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