Thermo Fisher Scientific Jagged1 Monoclonal Antibody (J.841.5)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

View 1 publication 1 publication

Immunoprecipitation (IP)

1:50

-

Product Specifications

Species Reactivity

Human, Mouse

Published species

Not Applicable

Host/Isotype

Rabbit / IgG

Class

Monoclonal

Type

Antibody

Clone

J.841.5

Immunogen

Synthetic peptide corresponding to residues surrounding Glu1140 (intracellular region) of human Jagged1 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Jagged1,uniProtId:P78504-1,ncbiNodeId:9606,antigenRange:1140,antigenLength:1218,antigenImageFileName:MA5-15012_Jagged1_P78504-1_Rabbit.svg,antigenImageFileNamePDP:MA5-15012_Jagged1_P78504-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

78 µg/mL

Purification

Affinity chromatography

Storage buffer

0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol

Contains

<0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_10986733

Product Specific Information

It is not recommended to aliquot this antibody.

This antibody is not cross-reactive with Jagged2.

Target Information

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.