Thermo Fisher Scientific N-WASP Monoclonal Antibody (C.427.3)
N-WASP 단백질을 인식하는 Rabbit Monoclonal 항체로, Western blot 및 Immunoprecipitation에 사용 가능. 다양한 종에 반응하며, 액상 형태로 제공. 고순도 친화 크로마토그래피 정제. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunoprecipitation (IP) | 1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Hamster, Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C.427.3 |
| Immunogen | Synthetic peptide corresponding to the sequence of human N-WASP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 8 µg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10984648 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structures and are involved in transducing signals from receptors on the cell surface to the actin cytoskeleton.
These proteins contain various motifs suggesting regulation by multiple stimuli and interactions with several proteins.
Studies show that WAS family proteins associate with the small GTPase Cdc42, which regulates actin filament formation, and the cytoskeletal organizing complex Arp2/3.
The WASL gene product, a homolog of WAS protein, is ubiquitously expressed with highest levels in neural tissues, binds Cdc42 directly, and induces formation of long actin microspikes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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