Thermo Fisher Scientific MCM8 Polyclonal Antibody
Thermo Fisher Scientific의 MCM8 Polyclonal Antibody는 인간 MCM8 단백질의 C-말단 펩타이드를 인식하는 토끼 IgG 항체입니다. Western blot과 IHC에 적합하며, 고순도의 액상 형태로 제공됩니다. DNA 복제 관련 연구에 활용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.2–1 µg/mL | View 2 publications |
| Immunohistochemistry (IHC) | 5 µg/mL | View 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal of human MCM8 (aa 717–766) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2576660 |
Product Specific Information
Peptide sequence:
IRLTEARARL ELREEATKED AEDIVEIMKY SMLGTYSDEF GNLDFERSQH
Sequence homology:
Cow: 100%
Dog: 93%
Guinea Pig: 100%
Horse: 100%
Human: 100%
Mouse: 100%
Rabbit: 100%
Rat: 100%
Zebrafish: 86%
Target Information
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) essential for the initiation of eukaryotic genome replication. The hexameric complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may participate in replication fork formation and recruitment of other DNA replication-related proteins.
This protein co-immunoprecipitates with MCM4, MCM6, and MCM7, suggesting interactions with other MCM proteins in DNA replication.
Alternatively spliced transcript variants encoding distinct isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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