Thermo Fisher Scientific MYZAP Polyclonal Antibody
MYOZAP 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 IHC에 적합. Human, Mouse, Rat에 반응하며, 항원 친화 크로마토그래피로 정제됨. PBS 버퍼에 0.02% sodium azide 포함, 2-8°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | An 18 amino acid peptide near the carboxy terminus of human MYOZAP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153152 |
Product Specific Information
- Suggested positive control: Rat kidney tissue lysate
- PA5-21116 can be used with blocking peptide PEP-1230
Target Information
MYOZAP (also known as GRINL1A) is a 54 kDa highly conserved cardiac protein strongly expressed in the heart and lung. It is a novel component of the intercalated disc and interacts with myosin phosphatase-RhoA interacting protein (MRIP), acting as an activator of Rho-dependent SRF signaling. Knockdown studies in zebrafish result in cardiomyopathy with severe dysfunction.
The MYOZAP gene is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A). Transcription occurs at an upstream promoter, with two groups of alternatively spliced variants: Gup (GRINL1A upstream transcripts) and Gcom (GRINL1A combined transcripts).
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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