Thermo Fisher Scientific ULBP2 Recombinant Rabbit Monoclonal Antibody (022)
ULBP2 단백질을 인식하는 재조합 토끼 단클론 항체로, IHC(P) 등 다양한 연구용 응용에 적합함. 높은 특이성과 감도를 제공하며, 로트 간 일관성 및 보존제 없는 포뮬레이션을 특징으로 함. 인간 ULBP2/N2DL-2에 특이적이며, 연구용으로만 사용 가능.
- 판매단위
- pk
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Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 022 |
| Immunogen | Recombinant Human ULBP2/N2DL-2 protein (Met1–Ser217) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2785465 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems clone specific antibody DNA sequences from immunoreactive rabbits, followed by screening of individual clones to select optimal candidates for production.
Advantages:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
This antibody shows specificity for Human ULBP2/N2DL-2.
Target Information
ULBP2 encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells, triggering release of cytokines and chemokines that recruit and activate NK cells. The mature protein is either membrane-anchored via a glycosylphosphatidylinositol moiety or secreted. Many malignant cells secrete this protein to evade NK cell immunosurveillance.
This gene is located in a cluster of multiple MHC class I-related genes on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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