Thermo Fisher Scientific TrxR1 Monoclonal Antibody (02)
Human TXNRD1 단백질을 인식하는 mouse monoclonal antibody입니다. Immunocytochemistry(ICC/IF)에 적합하며, 보존제가 포함되어 있지 않습니다. 단기 보관은 4°C, 장기 보관은 -20°C에서 권장됩니다. 연구용으로만 사용 가능합니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:20–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 02 |
| Immunogen | Recombinant Human TXNRD1 Protein (Tyr161–Cys647) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2785459 |
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human TXNRD1.
Target Information
This gene encodes a member of the family of pyridine nucleotide oxidoreductases. The protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress.
The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue required for catalytic activity.
The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3′ UTR of selenocysteine-containing genes has a common stem-loop structure, the SECIS element, necessary for recognizing UGA as a Sec codon rather than as a stop signal.
Alternative splicing results in several transcript variants encoding the same or different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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