Thermo Fisher Scientific SCN1B Polyclonal Antibody
SCN1B 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 인간에 반응하며, 합성 펩타이드로부터 제작되었습니다. 액상 형태로 0.5 mg/mL 농도이며, -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA541003
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human SCN1B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2608063 |
Product Specific Information
- Peptide sequence: NVTYNHSGDY ECHVYRLLFF ENYEHNTSVV KKIHIEVVDK ANRDMASIVS
- Sequence homology:
Cow: 93%
Dog: 100%
Guinea Pig: 100%
Horse: 93%
Human: 100%
Mouse: 93%
Rabbit: 100%
Rat: 100%
Target Information
Voltage-gated sodium channels are heteromeric proteins involved in generating and propagating action potentials in muscle and neuronal cells. They consist of one alpha and two beta subunits, where the alpha subunit provides channel activity and the beta-1 subunit modulates the kinetics of channel inactivation.
The SCN1B gene encodes a sodium channel beta-1 subunit. Mutations in this gene are associated with generalized epilepsy with febrile seizures plus, Brugada syndrome 5, and cardiac conduction defects. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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