Thermo Fisher Scientific NMDAR2C Polyclonal Antibody
Rabbit polyclonal antibody targeting human NMDAR2C (GRIN2C) N-terminal region. Validated for WB and IHC (Paraffin). Supplied as liquid, 0.5 mg/mL, affinity purified, stored at -20°C. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human GRIN2C (aa 69–118) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2607805 |
Product Specific Information
Peptide sequence:
VNTTNPSSLL TQICGLLGAA HVHGIVFEDN VDTEAVAQIL DFISSQTHVP
Sequence homology:
Cow: 93%
Dog: 93%
Guinea Pig: 93%
Human: 100%
Mouse: 100%
Rabbit: 86%
Rat: 100%
Zebrafish: 79%
Target Information
The NMDA Receptor (NMDAR) plays an essential role in memory and neuronal development, and has been implicated in several central nervous system disorders, including Alzheimer’s disease, epilepsy, and ischemic neuronal cell death. It is also a principal molecular target for alcohol in the CNS and is potentiated by protein phosphorylation. The NR1 protein can form NMDA-activated channels in Xenopus oocytes, but physiological channel characteristics are obtained when NR1 combines with one or more NMDAR2 (NR2 A–D) subunits.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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