Thermo Fisher Scientific COL22A1 Polyclonal Antibody
Human COL22A1 단백질을 인식하는 Rabbit Polyclonal Antibody. IHC, ICC/IF 등 다양한 응용에 적합. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. PBS 기반 완충액에 40% 글리세롤 포함. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human COL22A1. Recombinant protein control fragment (Product # RP-93895) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640020 |
Product Specific Information
Immunogen sequence:
LKEELEEIAS EPKSAHVFHV SDFNAIDKIR GKLRRRLCEN VLCPSVRVEG DRFKHTNGGT KEITGFDLMD LFSVKEILGK RENGAQSSYV RMG
Sequence identity:
Highest antigen sequence identity to orthologs: Mouse – 99%, Rat – 99%.
Target Information
This gene encodes a member of the collagen family that contributes to the stabilization of myotendinous junctions and strengthens skeletal muscle attachments during contractile activity. It belongs to the fibril-associated collagens with interrupted triple helix (FACIT) subset of the collagen superfamily, which associate with collagen fibers through their C-terminal collagenous domains and mediate protein-protein interactions through their N-terminal noncollagenous domains. The encoded protein is deposited in the basement membrane zone of the myotendinous junction, present at tissue junctions of muscles, tendons, heart, articular cartilage, and skin. Knockdown of the orthologous zebrafish gene induces muscular dystrophy by disruption of the myotendinous junction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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