Thermo Fisher Scientific C17orf71 Polyclonal Antibody
Thermo Fisher Scientific의 C17orf71 폴리클로날 항체는 인간 유래 단백질에 반응하며 IHC(P) 및 ICC/IF 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공되어 안정적인 장기 보관이 가능합니다. 연구용 전용 제품입니다.
- 카탈로그번호
- PA555202
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human C17orf71. Recombinant protein control fragment (Product #RP-93372). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2638833 |
Product Specific Information
Immunogen sequence:
SINCLFTVPA NQAFVYIVPG SQEEDPVGML LDQLRSHCTV KDPESLLVPA PLSGPRRYQV MRQHSRQQLS FHIDSSSSSS SGQLVDFTLR EFLWQHVELV LSKKGFDDSV GRNPQPSHFE LPTYQKWISA ASK
Sequence identity:
Highest antigen sequence identity to the following orthologs:
- Mouse: 97%
- Rat: 97%
Target Information
C17orf71 is involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. It is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex). Within this complex, it mediates the recruitment of SMG1 to the ribosome:SURF complex and suppresses SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC). It acts as a regulator of kinase activity. [UniProt]
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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