Thermo Fisher Scientific TRBP1 Polyclonal Antibody
Human TRBP1 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot 및 ELISA에 적합함. 고순도 Affinity Chromatography로 정제되어 높은 특이성과 재현성을 제공. PBS/glycerol buffer에 보관되며 -20°C에서 안정적 유지.
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- PA5120744
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1322–1621 of human TARBP1 (NP_005637.3) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.847 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914316 |
Product Specific Information
Immunogen sequence:
QVESMHGAGN AKKNWQRIQE HFFFATFHPL KDYCLETIFY ILPRLSGLIE DEWITIDKFT RFTDVPLAAG FQWYLSQTQL SKLKPGDWSQ QDIGTNLVEA DNQAEWTDVQ KKIIPWNSRV SDLDLELLFQ DRAARLGKSI SRLIVVASLI DKPTNLGGLC RTCEVFGASV LVVGSLQCIS DKQFQHLSVS AEQWLPLVEV KPPQLIDYLQ QKKTEGYTII GVEQTAKSLD LTQYCFPEKS LLLLGNEREG IPANLIQQLD VCVEIPQQGI IRSLNVHVSG ALLIWEYTRQ QLLSHGDTKP
Target Information
The human trans-activation response (TAR) RNA binding protein 1 (TRBP1) was initially identified as a protein that binds to the HIV-1 TAR RNA and activates the long terminal repeat (LTR) expression in the absence and presence of the viral trans-activator Tat.
This binding is enhanced by co-factors such as elongation factor 1-a (EF-1-a), polypyrimidine tract-binding protein (PTB), and the chaperonin-like protein stimulator of TAR RNA-binding proteins (SRB).
TRBP1 may act to disengage RNA polymerase II from TAR during transcriptional elongation if the RNA polymerase stalls at the TAR during transcriptional elongation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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