Thermo Fisher Scientific TRBP1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1322-1621 of human TARBP1 (NP_005637.3). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TRBP1,uniProtId:Q13395-1,ncbiNodeId:9606,antigenRange:1322-1621,antigenLength:1621,antigenImageFileName:PA5-120744_TRBP1_Q13395-1_Rabbit.svg,antigenImageFileNamePDP:PA5-120744_TRBP1_Q13395-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.847 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2914316

Product Specific Information

Immunogen sequence: QVESMHGAGN AKKNWQRIQE HFFFATFHPL KDYCLETIFY ILPRLSGLIE DEWITIDKFT RFTDVPLAAG FQWYLSQTQL SKLKPGDWSQ QDIGTNLVEA DNQAEWTDVQ KKIIPWNSRV SDLDLELLFQ DRAARLGKSI SRLIVVASLI DKPTNLGGLC RTCEVFGASV LVVGSLQCIS DKQFQHLSVS AEQWLPLVEV KPPQLIDYLQ QKKTEGYTII GVEQTAKSLD LTQYCFPEKS LLLLGNEREG IPANLIQQLD VCVEIPQQGI IRSLNVHVSG ALLIWEYTRQ QLLSHGDTKP

Target Information

The human trans-activation response (TAR) RNA binding protein 1 (TRBP1) was initially identified as a protein that binds to the HIV-1 TAR RNA and activates the long terminal repeat (LTR) expression in the absence and presence of the viral trans-activator Tat. This binding is enhanced by the presence of co-factors such as elongation factor 1-a (EF-1-a), polypyrimidine tract-binding protein (PTB), and the chaperonin-like protein stimulator of TAR RNA-binding proteins (SRB). TRBP1 may act to disengage RNA polymerase II from TAR during transcriptional elongation if the RNA polymerase stalls at the TAR during transcriptional elongation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.