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Thermo Fisher Scientific HTR2A Polyclonal Antibody
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HTR2A 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot, ICC/IF, ELISA에 적합합니다. Human 및 Mouse 시료에 반응하며, 고순도의 Affinity Chromatography로 정제되었습니다. 연구용으로만 사용 가능합니다.
- 판매단위
- pk
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마지막 업데이트 2025. 07. 27. 오전 10:50
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Thermo Fisher Scientific PA5120747 HTR2A Polyclonal Antibody 100 ul pk판매 단위 pk
재고 1개
710,700원VAT 포함 781,770원
Thermo Fisher Scientific · Thermo Fisher Scientific HTR2A Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 1–100 of human HTR2A (NP_000612.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.55 mg/mL |
| Purification | Affinity Chromatography |
| Storage buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2914319 |
Product Specific Information
- Positive test controls include: SH-SY5Y, Mouse brain.
- Immunogen sequence:
MDILCEENTS LSSTTNSLMQ LNDDTRLYSN DFNSGEANTS DAFNWTVDSE NRTNLSCEGC LSPSCLSLLH LQEKNWSALL TAVVIILTIA GNILVIMAVS
Target Information
Serotonin plays a major role in cardiovascular function and gastrointestinal motility. It mediates its effects through several G protein-coupled receptors, designated 5-HT (SR) receptors. The SR-2 receptors include SR-2A, SR-2B, and SR-2C subtypes, which activate phospholipase C and release intracellular calcium in response to serotonin.
- SR-2A: Involved in tracheal smooth muscle contraction, bronchoconstriction, and aldosterone production; associated with psychiatric disorders such as depression and schizophrenia.
- SR-2B: Expressed in cardiovascular tissues, gut, and brain; plays a role in cardiac pathology.
- SR-2C: Thought to mediate effects of atypical antipsychotic drugs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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