Thermo Fisher Scientific Phospho-MEK2 (Thr394) Polyclonal Antibody
Phospho-MEK2 (Thr394) 특이적 Rabbit Polyclonal Antibody로 Western blot, IHC, IP에 사용 가능. 인간 MEK2 Thr394 인산화 부위 유래 합성 펩타이드 면역원 사용. 고농도(1 mg/mL) 액상 형태, -20°C 저장. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Immunoprecipitation (IP) | Assay-Dependent |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide derived from human MEK2 around the phosphorylation site of Thr394 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2554742 |
Target Information
MAP2K2 (MEK2) is a dual specificity serine/threonine kinase that plays a critical role in mitogen growth factor signal transduction. MEK2 (MAPKK2) activates ERK1/2 and MAPK enzymes by phosphorylating threonine/glutamate/tyrosine (TEY) residues in the activation loop.
MEK1 and MEK2 are activated by dual phosphorylation on serine 218 and 222. Threonine 292 of MEK1 is phosphorylated by ERK2, forming a negative feedback loop that suppresses MEK1 activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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