Thermo Fisher Scientific Human HINT1 Synthetic Peptide
Human HINT1 단백질의 중심부 17개 아미노산 서열에 해당하는 합성 펩타이드입니다. PA5-20613 항체와 함께 블로킹 실험에 사용 가능합니다. 정제된 액상 형태로 제공되며 PBS 완충액에 0.1% BSA와 0.02% sodium azide를 포함합니다. 연구용으로만 사용됩니다.
- 카탈로그번호
- PEP0733
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Human HINT1 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 17 amino acids near the center of human HINT1.
PEP-0733 can be used as a blocking peptide with polyclonal antibody PA5-20613.
Target Information
Histidine triad nucleotide-binding protein 1 (HINT1) is a member of the histidine triad (HIT) protein family, a group of small nucleotide-binding and -hydrolyzing proteins.
HINT1 interacts with several diverse proteins and has been suggested to have tumor suppressive activities. It catalyzes the hydrolysis of adenosine 5'-monophoramidate substrates such as AMP-morpholidate, but its enzymatic function does not appear to play a role in its tumor suppression.
Recent experiments demonstrate that HINT1 forms a complex with POSH and JNK in vivo, inhibiting AP-1 activity and the phosphorylation of c-Jun, which may contribute to its tumor suppressor activity. Other studies raise the possibility of HINT1 as a candidate gene for schizophrenia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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