Thermo Fisher Scientific Mouse VEGF-165 Recombinant Protein, eBioscience

Applications

Tested Dilution

Publications

Control (Ctrl)

Assay-Dependent

-

Product Specifications

Species

Mouse

Expression System

E. coli

Amino acid sequence

Mouse VEGF-165 recombinant protein is homodimeric containing two 165 amino acid polypeptide chains

Molecular weight

39 kDa

Class

Recombinant

Type

Protein

Purity

>95%

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Purification

purified

Contains

no preservative

Storage conditions

-20°C

Shipping conditions

Wet ice

Product Specific Information

Description: Vascular Endothelial Cell Growth Factor (VEGF) is a homodimeric protein secreted by a variety of vascularized tissues. The reported activities of VEGF include stimulation of endothelial cell growth, angiogenesis and capillary permeability. Mouse VEGF is a 39 kDa homodimeric protein consisting of two 165 amino acid polypeptide chains.

Purity: >95%.

Molecular Weight: 39.0 kDa.

Target Information

The vascular endothelial growth factor (VEGF) family currently includes VEGF-A, VEGF-B, VEGF-C, VEGF-D, VEGF-E, and PIGF. VEGF and its receptor system have been shown to be the fundamental regulators in the cell signaling of angiogenesis. Most tumors have the absolute requirement of angiogenesis and VEGF has been described as the most potent angiogenic cytokine linked to this process. To date 5 different isoforms of VEGF have been described. These isoforms are generated as the result of alternative splicing from a single VEGF gene. These various isoforms have been shown to bind to two tyrosine-kinase receptors flt-1 (VEGFR-1) and flk-1/KDR (VEGFR-2), which have been found to be expressed almost exclusively on endothelial cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.