Thermo Fisher Scientific SIRP gamma Monoclonal Antibody (OX-119), PE
인간 SIRP gamma(CD172g)을 인식하는 마우스 단클론 항체로, PE 형광 표지된 제품입니다. Flow Cytometry에 적합하며 T세포, NK세포, 일부 B세포에서 발현되는 CD172g 검출에 사용됩니다. PBS 기반 완충액에 보관하며 4°C 암소 보관 권장.
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Applications
- Flow Cytometry (Flow): 10 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OX-119 |
| Immunogen | Recombinant human CD172g |
| Conjugate | PE |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2913051 |
Additional Formats
Product Specific Information
This antibody recognizes an extracellular epitope on CD172g, an approximately 55 kDa transmembrane glycoprotein expressed on most T cells, as well as on NK cells and some B cell populations.
Target Information
SIRP gamma (CD172g) recognizes a 55 kDa signal regulatory protein which is a member of the immunoglobulin gene superfamily.
SIRP gamma is expressed on most T lymphocytes and a subset of B cells, but is absent on myeloid cells.
CD172g has a truncated cytoplasmic tail similar to SIRP beta, but unlike SIRP beta, CD172g does not require DAP12 for surface expression.
Like SIRP alpha, CD172g binds to CD47 inducing apoptosis and is involved in negative regulation of receptor tyrosine kinase-coupled signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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