Thermo Fisher Scientific SQSTM1 Monoclonal Antibody (UMAB13), UltraMAB
SQSTM1 단백질을 인식하는 UMAB13 단클론 항체로, Western blot, ICC/IF, ChIP assay에 사용 가능. Human 특이성, Mouse IgG1 아이소타입. 고순도 친화 크로마토그래피 정제, PBS/BSA/glycerol 완충액에 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| ChIP assay (ChIP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB13 |
| Immunogen | Full-length human recombinant SQSTM1 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.0 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The SQSTM1 gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the NF-κB signaling pathway. It functions as a scaffolding/adaptor protein with TNF receptor-associated factor 6 to mediate NF-κB activation in response to upstream signals. Alternatively spliced transcript variants encoding the same or different isoforms have been identified. Mutations in this gene are associated with sporadic and familial Paget disease of bone.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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