Thermo Fisher Scientific ABCD1 Monoclonal Antibody (OTI2C12), TrueMAB
ABCD1 단백질을 인식하는 마우스 단일클론 항체로, Western blot 및 IHC(P) 실험에 적합합니다. 동결건조 형태로 제공되며, PBS 완충액에 8% 트레할로스가 포함되어 있습니다. 재구성 후 1 mg/mL 농도로 사용 가능하며, 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2C12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 508–745 of human ABCD1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The ABCD1 gene encodes a member of the UBA domain family, which includes proteins associated with ubiquitin and the ubiquitination pathway. The ubiquitin-associated domain is a non-covalent ubiquitin-binding domain consisting of a compact three-helix bundle.
This protein originates from a gene locus on chromosome 9, a region undergoing loss of heterozygosity in nasopharyngeal carcinoma (NPC). It is studied as a potential mutation target in NPC. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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