Thermo Fisher Scientific Phospho-PDGFRa (Tyr849) Polyclonal Antibody
PDGFRA의 Tyr849 인산화 부위를 인식하는 Rabbit Polyclonal Antibody로, WB 및 ICC/IF에 적합합니다. 인간, 마우스, 랫트 반응성이 있으며, 고순도 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PDGFRA (Accession P16234), corresponding to amino acid residues around phosphorylated Tyr849. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2816285 |
Product Specific Information
This antibody detects endogenous levels of PDGF Receptor alpha only when phosphorylated at Tyrosine 849.
Target Information
PDGFRA is a cell surface receptor tyrosine kinase that binds members of the platelet-derived growth factor family. These growth factors act as mitogens for cells of mesenchymal origin. The identity of the bound growth factor determines whether the receptor forms a homodimer or a heterodimer with PDGFRβ. Knockout mouse studies indicate that PDGFRA plays a crucial role in kidney development, as heterozygous mice exhibit defective kidney phenotypes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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