Thermo Fisher Scientific PIP1/WDR84 Polyclonal Antibody
Rabbit polyclonal antibody against human PIP1/WDR84 (PAK1IP1), suitable for WB and IP applications. Recognizes residues 342–392 of the target protein. Supplied as unconjugated liquid form at 0.20 mg/mL. Stored at 4°C; recommended shelf life 1 year.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 342 and 392 of Human PAK/PLC-interacting protein 1 (WD repeat protein 84) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which plays a positive role in signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 binds to the N-terminus of PAK1 and inhibits its activation by CDC42. May be involved in ribosomal large subunit assembly (PubMed:24120868). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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