Thermo Fisher Scientific C5AR1 Monoclonal Antibody (S5/1)
C5AR1 단백질을 인식하는 S5/1 클론의 Mouse Monoclonal Antibody. Western blot, IHC, Flow cytometry 등 다양한 응용에 적합. Human, Bovine 등 여러 종에 반응. 단백질 A로 정제된 액상 형태로, 4°C 단기 보관 가능.
- 카탈로그번호
- MA516937
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Flow Cytometry (Flow) | 1:50–1:100 |
| Functional Assay (Functional) | Assay-dependent |
Product Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Bovine, Ferret, Human, Mink, Rabbit |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | S5/1 |
| Immunogen | C5aR peptide: Met1–Asn31 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at −20°C avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2538414 |
Additional Formats
Product Specific Information
Predicted to react with mustelid based on sequence homology.
For FACS analysis, use 10 µL of the suggested working dilution to label 1×10^6 cells in 100 µL.
Target Information
CD88 (C5aR1) is a C5a Anaphylatoxin Receptor mediating effects of one of the most potent chemotactic agents. It is implicated in asthma and expressed in myeloid blood cells, brain, liver, lung, spleen, heart, kidney, and intestinal tract.
CD88 is the receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. It stimulates chemotaxis, granule enzyme release, and superoxide anion production.
CD88 participates in the classical complement pathway and may be involved in tissue injury associated with ischemia or sepsis, as well as the membrane attack complex.
Diseases associated with CD88 include Mannose-Binding Lectin Deficiency and Systemic Lupus Erythematosus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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