Thermo Fisher Scientific CIRBP Polyclonal Antibody
CIRBP 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, WB, IHC, ICC/IF 등 다양한 응용에 적합. 사람, 생쥐, 랫트 반응성. 고순도 친화 크로마토그래피 정제, 1 mg/mL 농도, PBS/50% glycerol 저장.
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Thermo Fisher Scientific CIRBP Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CIRBP (Accession Q14011), corresponding to amino acid residues Y141–E172 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899354 |
Product Specific Information
Antibody detects endogenous levels of total CIRBP.
Target Information
CIRBP is a cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival.
It acts as a translational activator and plays an essential role in cold-induced suppression of cell proliferation.
CIRBP specifically binds to the 3′-untranslated regions (3′-UTRs) of stress-responsive transcripts RPA2 and TXN.
When overexpressed, this protein acts as a translational repressor and promotes assembly of stress granules (SGs).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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