Thermo Fisher Scientific SERPINC1 Monoclonal Antibody (BDI205)
SERPINC1 단백질을 표적으로 하는 Thermo Fisher Scientific의 단클론 항체로, Human Antithrombin III에 특이적입니다. Western blot, ELISA, Neutralization, Affinity Purification 등에 사용 가능하며, 높은 특이성과 안정성을 제공합니다.
- 카탈로그번호
- MA127334
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific SERPINC1 Monoclonal Antibody (BDI205)
Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1–5 µg/mL | |
| ELISA | 1–5 µg/mL | |
| Neutralization (Neu) | Assay-dependent | |
| Affinity Purification (AP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | BDI205 |
| Immunogen | Human Antithrombin III |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_779265 |
Product Specific Information
MA1-27334 will not react with rabbit, bovine, or canine.
Target Information
The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. It inhibits thrombin and other activated serine proteases in the coagulation system, regulating the blood coagulation cascade.
This protein includes two functional domains:
- Heparin binding domain at the N-terminus
- Reactive site domain at the C-terminus
The inhibitory activity is enhanced by the presence of heparin. Over 120 mutations have been identified in this gene, many of which cause antithrombin-III deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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