Thermo Fisher Scientific ATP6V1A Polyclonal Antibody
ATP6V1A 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 제브라피시 반응성을 가지며 WB 및 IHC에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA5144619
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): Assay-dependent
- Immunohistochemistry (IHC): 1:50–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Zebrafish |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | The immunogen used to generate this antibody corresponds to zebrafish Atp6v1al. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.57 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090423 |
Target Information
ATP6V1A encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles.
V-ATPase dependent organelle acidification is necessary for intracellular processes such as:
- Protein sorting
- Zymogen activation
- Receptor-mediated endocytosis
- Synaptic vesicle proton gradient generation
V-ATPase consists of:
- V1 domain (cytosolic): Three A and three B subunits, two G subunits, plus C, D, E, F, and H subunits (contains ATP catalytic site)
- V0 domain (transmembrane): Five different subunits (a, c, c’, c”, and d)
Additional isoforms of many V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants.
This encoded protein is one of two V1 domain A subunit isoforms and is found in all tissues.
Transcript variants derived from alternative polyadenylation exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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