Thermo Fisher Scientific CCR7 Polyclonal Antibody
CCR7 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 다클론 항체로, Western blot, IHC, Flow cytometry, ELISA에 적합합니다. 인간 및 생쥐 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:250 |
| Flow Cytometry (Flow) | 1:10 |
| ELISA | 1:100,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues D(2) P G K P R K N V L V V A L L V I F Q V C(22) of mouse CCR7 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 1 mg/mL BSA |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2072904 |
Product Specific Information
- Recommended positive control: Mouse spleen
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
CCR7 is a member of the G protein-coupled receptor family, specifically the chemokine receptor subfamily. It is induced by Epstein-Barr virus (EBV) and mediates EBV effects on B lymphocytes. CCR7 is expressed in blood, bone marrow, lymph node, and intestine, particularly in lymphoid tissues and activated B and T lymphocytes. It regulates migration of memory T cells to inflamed tissues and promotes dendritic cell maturation. The chemokine ligand CCL19 (ECL) is a specific ligand for CCR7. Receptors in the C-C chemokine family include CCR1, CCR2A, CCR3, CCR4, CCR5, and the Duffy blood group antigen, which are important for T cell chemotaxis and phagocyte migration to inflammation sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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