Thermo Fisher Scientific LBP Monoclonal Antibody (RR433-8)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:50

-

ELISA (ELISA)

1:50

-

Functional Assay (Functional)

1:50

-

Product Specifications

Species Reactivity

Mouse

Host/Isotype

Rat / IgG2a

Class

Monoclonal

Type

Antibody

Clone

RR433-8

Immunogen

Murine natural and recombinant LBP. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:LBP,uniProtId:Q61805-1,ncbiNodeId:10090,antigenRange:1-481,antigenLength:481,antigenImageFileName:MA1-40030_LBP_Q61805-1_Rat.svg,antigenImageFileNamePDP:MA1-40030_LBP_Q61805-1_Rat_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Protein G

Storage buffer

PBS with 0.1% BSA

Contains

no preservative

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2138328

Product Specific Information

Endotoxin level < 24 EU/mg.

This antibody reacts highly specific with mouse natural and recombinant LBP. The antibody is a type II antibody blocking the LPS binding to CD14.
The MA1-40030 immunogen is mouse natural and recombinant LBP.

MA1-40030 detects LBP from mouse samples.

MA1-40030 has been successfully used in ELISA, Functional Assays and Western blot applications.

Target Information

The LBP protein is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP). Finally, this gene is found on chromosome 20, immediately downstream of the BPI gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.