Thermo Fisher Scientific Ubinuclein 1 Polyclonal Antibody

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human Ubinuclein 1 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Ubinuclein 1,uniProtId:Q9NPG3-1,ncbiNodeId:9606,antigenRange:587-675,antigenLength:1134,antigenImageFileName:PA5-64392_Ubinuclein_1_Q9NPG3-1_Rabbit.svg,antigenImageFileNamePDP:PA5-64392_Ubinuclein_1_Q9NPG3-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2649192

Product Specific Information

Immunogen sequence: AKKKVMAPSK IKVKESSTKP DKKVSVPSGQ IGGPIALPSD HQTGGLSIGA SSRELPSQAS GGLANPPPVN LEDSLDEDLI RNPASSVEA

Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 75%.

Target Information

Cellular senescence is a hallmark of tumor suppression and tissue aging. Senescent cells contain domains of heterochromatin, called senescence-associated heterochromatin foci (SAHF), that repress proliferation-promoting genes. The protein encoded by this gene binds to proliferation-promoting genes and is required for SAHF formation, enhancing methylation of histone H3.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.