Thermo Fisher Scientific FXYD2 Polyclonal Antibody
Human FXYD2 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:1,000~1:2,500 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. Na/K-ATPase γ 서브유닛 연구용.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 1:1,000–1:2,500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FXYD2. Recombinant protein control fragment (Product #RP-104136) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2641793 |
Product Specific Information
- Immunogen sequence: SRRFRCGGNK KRRQINEDEP
- Highest antigen sequence identity: Mouse – 75%, Rat – 75%
Target Information
The human FXYD2 (pronounced fix-id) gene maps to chromosome 11q23 and encodes the gamma subunit of Na/K-ATPase (NKA).
FXYD2 gamma subunit modulates NKA activity by inducing ion channel activity.
The mammalian FXYD family maintains Na⁺ and K⁺ gradients between intracellular and extracellular milieus of cells in processes such as renal Na⁺ reabsorption, muscle contraction, and neuronal excitability.
FXYDs are single-span membrane proteins sharing a 35 amino acid signature domain beginning with the sequence PFXYD, containing 7 invariant and 6 conserved amino acids.
Other members of the FXYD family include:
- FXYD1 (PLM, phospholemman)
- FXYD3 (Mat8, mammary tumor protein 8)
- FXYD4 (CHIF)
- FXYD5 (RIC)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-64387_FXYD2_P54710-1_Rabbit.svg, PA5-64387_FXYD2_P54710-1_Rabbit_PDP.jpeg)
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